Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
S100B | P04271 | S100 calcium binding protein B | Calcium-binding protein | 4.4E-02 | 0.383 | 0.923 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
ATN1 | P54259 | atrophin 1 | 1.00 | 0.409 | 0.885 | |
NCAM1 | P13591 | neural cell adhesion molecule 1 | 1.00 | 0.415 | 0.885 |