Disease: Spasticity, CTCAE
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
VPS13D Q5THJ4 vacuolar protein sorting 13 homolog D 1.1E-06 0.769 0.346
UBA5 Q9GZZ9 ubiquitin like modifier activating enzyme 5 Enzyme 2.5E-04 0.582 0.731
UFM1 P61960 ubiquitin fold modifier 1 0.16 0.722 0.385
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
WARS2 Q9UGM6 tryptophanyl tRNA synthetase 2, mitochondrial 5.1E-02 0.617 0.577
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
TBP P20226 TATA-box binding protein Transcription factor 1.5E-02 0.552 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692
SYNGAP1 Q96PV0 synaptic Ras GTPase activating protein 1 Enzyme modulator 1.00 0.584 0.577
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPTBN2 O15020 spectrin beta, non-erythrocytic 2 9.9E-05 0.619 0.731
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
SNX14 Q9Y5W7 sorting nexin 14 Enzyme modulator 6.1E-17 0.659 0.423
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SIL1 Q9H173 SIL1 nucleotide exchange factor 1.2E-02 0.584 0.731
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SCYL1 Q96KG9 SCY1 like pseudokinase 1 Kinase 2.5E-08 0.582 0.769
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654