Disease: Neurodegenerative Disorders
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC52A2 Q9HAB3 solute carrier family 52 member 2 Transporter 2.5E-03 0.483 0.808
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
SLC25A46 Q96AG3 solute carrier family 25 member 46 Transporter 1.3E-05 0.695 0.308
SIL1 Q9H173 SIL1 nucleotide exchange factor 1.2E-02 0.584 0.731
SGCG Q13326 sarcoglycan gamma Cellular structure 4.8E-05 0.621 0.615
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SCYL1 Q96KG9 SCY1 like pseudokinase 1 Kinase 2.5E-08 0.582 0.769
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SCA26 spinocerebellar ataxia 26
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
RPSA P08865 ribosomal protein SA Nucleic acid binding 0.93 0.485 0.769
RPS4X P62701 ribosomal protein S4 X-linked Nucleic acid binding 0.93 0.711 0.500
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
RGS6 P49758 regulator of G protein signaling 6 0.44 0.564 0.769
RELN P78509 reelin 1.00 0.515 0.731
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923