Disease: Thrombocythemia, Essential
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCL2L2 Q92843 BCL2 like 2 Signaling 0.47 0.599 0.615
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846
H2AX P16104 H2A.X variant histone Nucleic acid binding 0.18 0.484 0.808
HAVCR2 Q8TDQ0 hepatitis A virus cellular receptor 2 3.9E-02 0.450 0.808
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
ITGA2B P08514 integrin subunit alpha 2b 1.5E-16 0.493 0.692
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885