Disease: keratoacanthoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
S100A9 P06702 S100 calcium binding protein A9 Calcium-binding protein 0.48 0.433 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923