Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
H3P23 | H3 histone pseudogene 23 | 0.443 | 0.769 | |||
PSMD9 | O00233 | proteasome 26S subunit, non-ATPase 9 | Enzyme modulator | 4.9E-06 | 0.435 | 0.846 |
DCTN6 | O00399 | dynactin subunit 6 | Cellular structure | 5.6E-02 | 0.442 | 0.769 |
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
TP73 | O15350 | tumor protein p73 | Transcription factor | 1.00 | 0.449 | 0.808 |
ZNRD2 | O60232 | zinc ribbon domain containing 2 | 1.8E-07 | 0.443 | 0.769 | |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
CXCL10 | P02778 | C-X-C motif chemokine ligand 10 | Signaling | 0.37 | 0.378 | 0.885 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TYMS | P04818 | thymidylate synthetase | Enzyme | 0.72 | 0.425 | 0.846 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
PCNA | P12004 | proliferating cell nuclear antigen | Nucleic acid binding | 0.98 | 0.382 | 0.846 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
PAX1 | P15863 | paired box 1 | 0.70 | 0.593 | 0.654 |