Disease: Charcot-Marie-Tooth Disease, Type Ia (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CNTF P26441 ciliary neurotrophic factor 2.3E-05 0.561 0.615
HOXD10 P28358 homeobox D10 6.3E-02 0.590 0.538
MPZ P25189 myelin protein zero 0.27 0.503 0.846
NEFL P07196 neurofilament light 0.488 0.769
RNMT O43148 RNA guanine-7 methyltransferase 5.7E-05 0.647 0.500
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731
RER1 O15258 retention in endoplasmic reticulum sorting receptor 1 0.38 0.821 0.231
MORC2 Q9Y6X9 MORC family CW-type zinc finger 2 1.00 0.626 0.462
LRSAM1 Q6UWE0 leucine rich repeat and sterile alpha motif containing 1 3.1E-13 0.638 0.500
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
CANX P27824 calnexin Chaperone 0.87 0.582 0.769
COX10 Q12887 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 Enzyme 8.4E-02 0.623 0.654
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
NDRG1 Q92597 N-myc downstream regulated 1 Enzyme 1.1E-02 0.488 0.731
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
MAG P20916 myelin associated glycoprotein Receptor 0.49 0.579 0.692
PXMP2 Q9NR77 peroxisomal membrane protein 2 Receptor 9.2E-03 0.743 0.192
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808
LITAF Q99732 lipopolysaccharide induced TNF factor Transcription factor 3.1E-02 0.650 0.462
SLC25A46 Q96AG3 solute carrier family 25 member 46 Transporter 1.3E-05 0.695 0.308