Disease: Sensorimotor neuropathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AIFM1 O95831 apoptosis inducing factor mitochondria associated 1 Enzyme 1.00 0.527 0.769
ATP1A1 P05023 ATPase Na+/K+ transporting subunit alpha 1 Transporter 1.00 0.601 0.808
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
BAG3 O95817 BAG cochaperone 3 0.62 0.498 0.846
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
HADHB P55084 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta Enzyme 1.5E-11 0.619 0.692
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
IGHMBP2 P38935 immunoglobulin mu DNA binding protein 2 3.0E-16 0.636 0.615
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
MAG P20916 myelin associated glycoprotein Receptor 0.49 0.579 0.692
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MPZ P25189 myelin protein zero 0.27 0.503 0.846
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
NEFL P07196 neurofilament light 0.488 0.769
PDK3 Q15120 pyruvate dehydrogenase kinase 3 Kinase 0.45 0.678 0.500
PNKP Q96T60 polynucleotide kinase 3'-phosphatase 3.7E-14 0.553 0.692
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
RFC1 P35251 replication factor C subunit 1 0.97 0.541 0.808
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
SBF2 Q86WG5 SET binding factor 2 Enzyme 6.4E-10 0.619 0.577
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SH3TC2 Q8TF17 SH3 domain and tetratricopeptide repeats 2 8.3E-16 0.666 0.385