Disease: Peripheral axonal neuropathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
FBLN5 Q9UBX5 fibulin 5 Calcium-binding protein 1.00 0.546 0.692
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
HADHB P55084 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta Enzyme 1.5E-11 0.619 0.692
HARS1 P12081 histidyl-tRNA synthetase 1 Enzyme 2.4E-06 0.569 0.808
HARS2 P49590 histidyl-tRNA synthetase 2, mitochondrial Enzyme 2.8E-05 0.705 0.462
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
LMNA P02545 lamin A/C 1.00 0.384 0.885
MAD2L1BP Q15013 MAD2L1 binding protein 1.4E-08 0.623 0.577
MARS1 P56192 methionyl-tRNA synthetase 1 2.1E-15 0.638 0.654
MCM3AP O60318 minichromosome maintenance complex component 3 associated protein 5.2E-09 0.647 0.654
MED25 Q71SY5 mediator complex subunit 25 Transcription factor 8.4E-07 0.582 0.654
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MPZ P25189 myelin protein zero 0.27 0.503 0.846
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
NEFL P07196 neurofilament light 0.488 0.769
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731