Disease: Mental Retardation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
FOXC1 Q12948 forkhead box C1 Transcription factor 0.95 0.483 0.846
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
FOXL2 P58012 forkhead box L2 Transcription factor 0.88 0.542 0.692
FOXP2 O15409 forkhead box P2 1.00 0.545 0.808
FRAXA fragile site, folic acid type, rare, fra(X)(q27.3) A (macroorchidism, mental retardation) 0.641 0.462
FRAXE fragile site, folic acid type, rare, fra(X)(q28) E 0.636 0.462
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
LONP1 P36776 lon peptidase 1, mitochondrial Enzyme 1.00 0.517 0.808
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
KMT2B Q9UMN6 lysine methyltransferase 2B 1.00 0.529 0.808
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808
MED13L Q71F56 mediator complex subunit 13L 1.00 0.617 0.538
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NIPBL Q6KC79 NIPBL cohesin loading factor Nucleic acid binding 1.00 0.521 0.808
NUFIP2 Q7Z417 nuclear FMR1 interacting protein 2 1.00 0.641 0.577