Disease: Mental Retardation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
KCNH1 O95259 potassium voltage-gated channel subfamily H member 1 Ion channel 0.55 0.542 0.731
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
RAI1 Q7Z5J4 retinoic acid induced 1 Transcription factor 1.00 0.545 0.731
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
DOCK8 Q8NF50 dedicator of cytokinesis 8 Enzyme modulator 1.5E-11 0.578 0.731
SHANK3 Q9BYB0 SH3 and multiple ankyrin repeat domains 3 1.00 0.550 0.731
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
ANOS1 P23352 anosmin 1 1.00 0.537 0.769
PAX6 P26367 paired box 6 1.00 0.450 0.769
PMM2 O15305 phosphomannomutase 2 Enzyme 1.4E-17 0.535 0.769
TBX3 O15119 T-box transcription factor 3 Transcription factor 0.99 0.525 0.769
TGIF1 Q15583 TGFB induced factor homeobox 1 Enzyme 1.0E-02 0.588 0.769
UROD P06132 uroporphyrinogen decarboxylase 1.3E-08 0.521 0.769
VPS13B Q7Z7G8 vacuolar protein sorting 13 homolog B 2.5E-45 0.579 0.769
NR0B1 P51843 nuclear receptor subfamily 0 group B member 1 Nuclear receptor 0.97 0.494 0.808
ARSD P51689 arylsulfatase D Enzyme 1.6E-03 0.535 0.808
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
OPN1LW P04000 opsin 1, long wave sensitive G-protein coupled receptor 0.98 0.497 0.808
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808