Disease: Cholestasis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
ALB P02768 albumin Transporter 0.64 0.317 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
IL2 P60568 interleukin 2 0.48 0.336 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
MIR21 microRNA 21 0.363 0.846
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923