Disease: Childhood Soft Tissue Sarcoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCC1 P33527 ATP binding cassette subfamily C member 1 Transporter 1.2E-03 0.445 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
CSPG4 Q6UVK1 chondroitin sulfate proteoglycan 4 2.6E-05 0.599 0.615
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FSD1 Q9BTV5 fibronectin type III and SPRY domain containing 1 0.25 0.486 0.808
FSD1L Q9BXM9 fibronectin type III and SPRY domain containing 1 like 0.23 0.488 0.808
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769