Disease: Turcot syndrome (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALCAM Q13740 activated leukocyte cell adhesion molecule Cell adhesion 0.73 0.502 0.808
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MIR148A microRNA 148a 0.506 0.846
MIR155 microRNA 155 0.384 0.885
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962