Disease: Advanced breast cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCC1 P33527 ATP binding cassette subfamily C member 1 Transporter 1.2E-03 0.445 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CD276 Q5ZPR3 CD276 molecule Enzyme modulator 2.5E-09 0.505 0.731
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
MIR155 microRNA 155 0.384 0.885
MIR222 microRNA 222 0.486 0.808
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885