Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |
HLA-DRB1 | P01911 | major histocompatibility complex, class II, DR beta 1 | Immune response | 1.1E-03 | 0.333 | 0.923 |
AHR | P35869 | aryl hydrocarbon receptor | Transcription factor | 1.00 | 0.410 | 0.923 |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
TNFRSF1A | P19438 | TNF receptor superfamily member 1A | 0.99 | 0.409 | 0.923 | |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
NOD2 | Q9HC29 | nucleotide binding oligomerization domain containing 2 | Enzyme | 2.0E-30 | 0.423 | 0.923 |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
PLAU | P00749 | plasminogen activator, urokinase | Enzyme | 2.3E-06 | 0.425 | 0.923 |
IL2RA | P01589 | interleukin 2 receptor subunit alpha | Receptor | 5.5E-02 | 0.389 | 0.885 |
ATG5 | Q9H1Y0 | autophagy related 5 | Transporter | 0.98 | 0.462 | 0.885 |
PRKCB | P05771 | protein kinase C beta | Kinase | 1.00 | 0.453 | 0.885 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
ITGAL | P20701 | integrin subunit alpha L | 4.3E-03 | 0.511 | 0.885 | |
MST1 | P26927 | macrophage stimulating 1 | Enzyme | 4.8E-19 | 0.465 | 0.885 |
CD28 | P10747 | CD28 molecule | 0.36 | 0.436 | 0.885 | |
HLA-DQA1 | P01909 | major histocompatibility complex, class II, DQ alpha 1 | Immune response | 2.4E-02 | 0.416 | 0.846 |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
IL6R | P08887 | interleukin 6 receptor | Signaling | 3.2E-05 | 0.471 | 0.846 |
DNMT3A | Q9Y6K1 | DNA methyltransferase 3 alpha | 7.4E-39 | 0.445 | 0.846 | |
CD40 | P25942 | CD40 molecule | 0.85 | 0.396 | 0.846 | |
ACTA2 | P62736 | actin alpha 2, smooth muscle | Cellular structure | 0.93 | 0.508 | 0.846 |
CCL20 | P78556 | C-C motif chemokine ligand 20 | Signaling | 2.4E-04 | 0.474 | 0.846 |