Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
SOX2 | P48431 | SRY-box transcription factor 2 | Transcription factor | 0.71 | 0.405 | 0.808 |
BMP4 | P12644 | bone morphogenetic protein 4 | Signaling | 0.96 | 0.422 | 0.808 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
ABCB6 | Q9NP58 | ATP binding cassette subfamily B member 6 (Langereis blood group) | Transporter | 8.6E-19 | 0.431 | 0.885 |
YAP1 | P46937 | Yes associated protein 1 | Enzyme modulator | 1.00 | 0.432 | 0.808 |
TGFB2 | P61812 | transforming growth factor beta 2 | Signaling | 1.00 | 0.433 | 0.885 |
CHD7 | Q9P2D1 | chromodomain helicase DNA binding protein 7 | 1.00 | 0.441 | 0.846 | |
BCL6 | P41182 | BCL6 transcription repressor | 0.96 | 0.444 | 0.808 | |
PAX6 | P26367 | paired box 6 | 1.00 | 0.450 | 0.769 | |
CYP1B1 | Q16678 | cytochrome P450 family 1 subfamily B member 1 | Enzyme | 2.2E-05 | 0.457 | 0.769 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
HDAC1 | Q13547 | histone deacetylase 1 | Epigenetic regulator | 0.61 | 0.460 | 0.846 |
KMT2D | O14686 | lysine methyltransferase 2D | 1.00 | 0.465 | 0.808 | |
RARA | P10276 | retinoic acid receptor alpha | Nuclear receptor | 0.96 | 0.470 | 0.846 |
BCOR | Q6W2J9 | BCL6 corepressor | 1.00 | 0.471 | 0.808 | |
ZEB2 | O60315 | zinc finger E-box binding homeobox 2 | Transcription factor | 1.00 | 0.471 | 0.808 |
ACTG1 | P63261 | actin gamma 1 | Cellular structure | 4.8E-03 | 0.477 | 0.846 |
RARB | P10826 | retinoic acid receptor beta | Nuclear receptor | 1.00 | 0.478 | 0.846 |
FOXC1 | Q12948 | forkhead box C1 | Transcription factor | 0.95 | 0.483 | 0.846 |