Disease: Colorectal Neoplasms
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
AXIN2 Q9Y2T1 axin 2 0.57 0.507 0.692
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
LGR5 O75473 leucine rich repeat containing G protein-coupled receptor 5 G-protein coupled receptor 2.5E-08 0.542 0.654
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
ODC1 P11926 ornithine decarboxylase 1 Enzyme 0.17 0.510 0.731
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
SERPINB5 P36952 serpin family B member 5 Enzyme modulator 3.6E-03 0.582 0.577
SLC19A1 P41440 solute carrier family 19 member 1 Transporter 6.5E-06 0.523 0.692
SLCO1B3 Q9NPD5 solute carrier organic anion transporter family member 1B3 Transporter 5.3E-24 0.592 0.769
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SPARC P09486 secreted protein acidic and cysteine rich Signaling 0.89 0.445 0.846
SRC P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 1.00 0.467 0.885