Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
BRD4 | O60885 | bromodomain containing 4 | Epigenetic regulator | 1.00 | 0.446 | 0.885 |
CCNH | P51946 | cyclin H | Enzyme modulator | 8.1E-04 | 0.595 | 0.769 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
GRIK2 | Q13002 | glutamate ionotropic receptor kainate type subunit 2 | Ion channel | 1.00 | 0.561 | 0.769 |
HES1 | Q14469 | hes family bHLH transcription factor 1 | Transcription factor | 0.71 | 0.468 | 0.885 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
MACIR | Q96GV9 | macrophage immunometabolism regulator | 0.43 | 0.691 | 0.462 | |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
PROM1 | O43490 | prominin 1 | Transporter | 1.9E-22 | 0.410 | 0.846 |
RECK | O95980 | reversion inducing cysteine rich protein with kazal motifs | Enzyme modulator | 1.9E-10 | 0.547 | 0.731 |
TNFSF10 | P50591 | TNF superfamily member 10 | Signaling | 0.13 | 0.413 | 0.885 |
TP53BP1 | Q12888 | tumor protein p53 binding protein 1 | Epigenetic regulator | 1.00 | 0.520 | 0.731 |
TRMT11 | Q7Z4G4 | tRNA methyltransferase 11 homolog | 3.9E-12 | 0.729 | 0.269 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
WT1 | P19544 | WT1 transcription factor | Nucleic acid binding | 1.00 | 0.422 | 0.808 |