Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
DPYD | Q12882 | dihydropyrimidine dehydrogenase | Enzyme | 3.4E-22 | 0.493 | 0.846 |
ERCC2 | P18074 | ERCC excision repair 2, TFIIH core complex helicase subunit | Enzyme | 7.1E-20 | 0.420 | 0.846 |
MUTYH | Q9UIF7 | mutY DNA glycosylase | Enzyme | 1.3E-18 | 0.521 | 0.769 |
SELENBP1 | Q13228 | selenium binding protein 1 | Immune response | 3.2E-16 | 0.493 | 0.846 |
XAF1 | Q6GPH4 | XIAP associated factor 1 | 6.8E-12 | 0.587 | 0.769 | |
KRT20 | P35900 | keratin 20 | 9.1E-11 | 0.388 | 0.846 | |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
WIF1 | Q9Y5W5 | WNT inhibitory factor 1 | Calcium-binding protein | 1.3E-09 | 0.507 | 0.731 |
CYP2A6 | P11509 | cytochrome P450 family 2 subfamily A member 6 | 5.4E-09 | 0.556 | 0.731 | |
XRCC1 | P18887 | X-ray repair cross complementing 1 | 6.3E-09 | 0.421 | 0.923 | |
CASP8 | Q14790 | caspase 8 | Enzyme | 3.7E-06 | 0.404 | 0.923 |
DPAGT1 | Q9H3H5 | dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 | Enzyme | 1.1E-05 | 0.621 | 0.538 |
UMPS | P11172 | uridine monophosphate synthetase | 1.1E-04 | 0.584 | 0.615 | |
TYMP | P19971 | thymidine phosphorylase | Enzyme | 1.2E-04 | 0.495 | 0.769 |
PYCARD | Q9ULZ3 | PYD and CARD domain containing | Enzyme | 2.0E-04 | 0.457 | 0.808 |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
PPARG | P37231 | peroxisome proliferator activated receptor gamma | Nuclear receptor | 2.9E-02 | 0.358 | 0.885 |
BIRC5 | O15392 | baculoviral IAP repeat containing 5 | Enzyme modulator | 5.6E-02 | 0.495 | 0.731 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
SOD2 | P04179 | superoxide dismutase 2 | Enzyme | 0.15 | 0.379 | 0.923 |
TNFRSF9 | Q07011 | TNF receptor superfamily member 9 | 0.32 | 0.502 | 0.769 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
FADS1 | O60427 | fatty acid desaturase 1 | 0.37 | 0.582 | 0.769 |