Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
FGFR3 | P22607 | fibroblast growth factor receptor 3 | Kinase | 1.6E-05 | 0.391 | 0.846 |
STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
PRPS1 | P60891 | phosphoribosyl pyrophosphate synthetase 1 | Kinase | 0.92 | 0.584 | 0.731 |
SETBP1 | Q9Y6X0 | SET binding protein 1 | 1.00 | 0.503 | 0.808 | |
EPHA3 | P29320 | EPH receptor A3 | Kinase | 1.2E-05 | 0.497 | 0.692 |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
SCNN1B | P51168 | sodium channel epithelial 1 subunit beta | Ion channel | 5.8E-08 | 0.628 | 0.577 |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
ERCC6 | P0DP91 Q03468 | ERCC excision repair 6, chromatin remodeling factor | 5.2E-22 | 0.507 | 0.808 | |
DMD | P11532 | dystrophin | 1.00 | 0.423 | 0.923 | |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
CDKL5 | O76039 | cyclin dependent kinase like 5 | Kinase | 1.00 | 0.522 | 0.692 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
DCC | P43146 | DCC netrin 1 receptor | 0.99 | 0.471 | 0.808 | |
FN1 | P02751 | fibronectin 1 | Signaling | 1.4E-03 | 0.365 | 0.962 |