Disease: Alcohol Use Disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846
ADH1C P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide Enzyme 0.547 0.731
AKR1A1 P14550 aldo-keto reductase family 1 member A1 Enzyme 6.7E-07 0.510 0.846
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885
DDX53 Q86TM3 DEAD-box helicase 53 0.66 0.568 0.846
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
HDAC1 Q13547 histone deacetylase 1 Epigenetic regulator 0.61 0.460 0.846
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885