Disease: 21-hydroxylase deficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
CAPN10 Q9HC96 calpain 10 Enzyme 6.9E-13 0.621 0.577
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
POR P16435 cytochrome p450 oxidoreductase 3.4E-10 0.502 0.769
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
GLO1 Q04760 glyoxalase I 9.7E-07 0.537 0.769
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
NR3C2 P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 0.84 0.469 0.846
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808