Disease: Abetalipoproteinemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
CRLF2 Q9HC73 cytokine receptor like factor 2 Signaling 3.3E-07 0.615 0.538
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
H3P9 H3 histone pseudogene 9 0.505 0.731
HDL3 Huntington-like neurodegenerative disorder 2 0.663 0.423
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
JPH3 Q8WXH2 junctophilin 3 1.00 0.608 0.538
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MRPL28 Q13084 mitochondrial ribosomal protein L28 2.0E-07 0.505 0.731
MTTP P55157 microsomal triglyceride transfer protein Transporter 1.0E-05 0.505 0.846
MYB P10242 MYB proto-oncogene, transcription factor 0.82 0.490 0.692
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885
NXT1 Q9UKK6 nuclear transport factor 2 like export factor 1 0.65 0.505 0.731
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
PIK3C2A O00443 phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Kinase 1.0E-02 0.633 0.692