Disease: Anemia, Sickle Cell
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NM neutrophil migration 0.473 0.808
UGT1A UDP glucuronosyltransferase family 1 member A complex locus 0.540 0.654
UGT1A10 Q9HAW8 UDP glucuronosyltransferase family 1 member A10 4.6E-19 0.588 0.615
CHIT1 Q13231 chitinase 1 7.2E-16 0.525 0.692
ITGB2 P05107 integrin subunit beta 2 Receptor 5.1E-15 0.444 0.923
UGT1A7 Q9HAW7 UDP glucuronosyltransferase family 1 member A7 8.7E-14 0.550 0.692
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885
UGGT1 Q9NYU2 UDP-glucose glycoprotein glucosyltransferase 1 Enzyme 5.2E-10 0.682 0.385
UGT1A8 Q9HAW9 UDP glucuronosyltransferase family 1 member A8 1.3E-09 0.588 0.654
UGT1A3 P35503 UDP glucuronosyltransferase family 1 member A3 1.3E-09 0.623 0.538
UGT1A5 P35504 UDP glucuronosyltransferase family 1 member A5 9.4E-09 0.656 0.462
UGT1A9 O60656 UDP glucuronosyltransferase family 1 member A9 5.4E-08 0.590 0.577
FCGR3B O75015 Fc fragment of IgG receptor IIIb Cell adhesion 3.0E-07 0.452 0.962
UGT1A6 P19224 UDP glucuronosyltransferase family 1 member A6 3.0E-07 0.560 0.654
UGT1A4 P22310 UDP glucuronosyltransferase family 1 member A4 6.0E-07 0.595 0.654
FCGR2A P12318 Fc fragment of IgG receptor IIa Cell adhesion 2.0E-06 0.480 0.769
UGT1A1 P22309 UDP glucuronosyltransferase family 1 member A1 3.3E-06 0.464 0.769
FCGR3A P08637 Fc fragment of IgG receptor IIIa Cell adhesion 3.7E-06 0.432 0.962
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885
PTX3 P26022 pentraxin 3 7.0E-05 0.457 0.808
ARG1 P05089 arginase 1 Enzyme 3.6E-04 0.476 0.846
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962