Disease: Malignant neoplasm of soft tissue
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
TMED7 Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 0.48 0.436 0.808
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
MGA Q8IWI9 MAX dimerization protein MGA Transcription factor 1.00 0.711 0.423
MAML3 Q96JK9 mastermind like transcriptional coactivator 3 Transcription factor 1.00 0.653 0.577
MAML2 Q8IZL2 mastermind like transcriptional coactivator 2 Transcription factor 1.00 0.592 0.577
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VEGFC P49767 vascular endothelial growth factor C Signaling 0.50 0.459 0.769
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
EWSR1 Q01844 EWS RNA binding protein 1 Nucleic acid binding 1.00 0.474 0.692
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923