Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
ARID1A | O14497 | AT-rich interaction domain 1A | 1.00 | 0.455 | 0.846 | |
DAPK1 | P53355 | death associated protein kinase 1 | Kinase | 1.00 | 0.472 | 0.808 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
JAG1 | P78504 | jagged canonical Notch ligand 1 | 1.00 | 0.429 | 0.808 | |
AQP1 | P29972 | aquaporin 1 (Colton blood group) | Ion channel | 2.6E-07 | 0.467 | 0.885 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
KRT5 | P13647 | keratin 5 | 0.64 | 0.512 | 0.731 | |
KMT2C | Q8NEZ4 | lysine methyltransferase 2C | 1.00 | 0.558 | 0.692 | |
ITGB4 | P16144 | integrin subunit beta 4 | Receptor | 9.5E-19 | 0.525 | 0.731 |
SETD2 | Q9BYW2 | SET domain containing 2, histone lysine methyltransferase | Epigenetic regulator | 1.00 | 0.424 | 0.846 |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
FANCA | O15360 | FA complementation group A | 1.6E-68 | 0.505 | 0.731 | |
BCL11A | Q9H165 | BAF chromatin remodeling complex subunit BCL11A | Transcription factor | 0.97 | 0.541 | 0.769 |
FOXP2 | O15409 | forkhead box P2 | 1.00 | 0.545 | 0.808 | |
MYCN | P04198 | MYCN proto-oncogene, bHLH transcription factor | Transcription factor | 0.89 | 0.454 | 0.808 |
TOP2A | P11388 | DNA topoisomerase II alpha | 0.99 | 0.497 | 0.731 |