Disease: Giant Cell Tumor of Bone
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
CCL20 P78556 C-C motif chemokine ligand 20 Signaling 2.4E-04 0.474 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CD276 Q5ZPR3 CD276 molecule Enzyme modulator 2.5E-09 0.505 0.731
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
DCN P07585 decorin 0.31 0.457 0.808
DPT Q07507 dermatopontin Extracellular structure 4.3E-06 0.641 0.654
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
UVRAG Q9P2Y5 UV radiation resistance associated 0.99 0.436 0.769