Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB11 O95342 ATP binding cassette subfamily B member 11 Transporter 1.6E-12 0.566 0.654
ACACA Q13085 acetyl-CoA carboxylase alpha 1.00 0.480 0.846
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692
ACCS Q96QU6 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Enzyme 9.0E-07 0.522 0.731
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACSS2 Q9NR19 acyl-CoA synthetase short chain family member 2 Enzyme 1.1E-13 0.506 0.808
ALB P02768 albumin Transporter 0.64 0.317 0.962
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
GCG P01275 glucagon 3.5E-02 0.431 0.885
GPER1 Q99527 G protein-coupled estrogen receptor 1 G-protein coupled receptor 0.57 0.505 0.731
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
HBA1 P69905 hemoglobin subunit alpha 1 6.7E-03 0.508 0.808
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923