Disease: Polycystic Kidney, Autosomal Dominant
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ALB P02768 albumin Transporter 0.64 0.317 0.962
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
AQP2 P41181 aquaporin 2 Ion channel 2.5E-06 0.581 0.769
AQP3 Q92482 aquaporin 3 (Gill blood group) Ion channel 0.13 0.546 0.769
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
AVPR2 P30518 arginine vasopressin receptor 2 G-protein coupled receptor 0.56 0.568 0.769
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
CLDN7 O95471 claudin 7 Cell-cell junction 2.9E-03 0.494 0.808
DNER Q8NFT8 delta/notch like EGF repeat containing 0.19 0.493 0.769
DUOX2 Q9NRD8 dual oxidase 2 Enzyme 4.5E-56 0.533 0.769
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
HBA1 P69905 hemoglobin subunit alpha 1 6.7E-03 0.508 0.808
HBA2 P69905 hemoglobin subunit alpha 2 3.1E-03 0.512 0.808
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923