Disease: Agenesis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
ACACA Q13085 acetyl-CoA carboxylase alpha 1.00 0.480 0.846
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
BMS1 Q14692 BMS1 ribosome biogenesis factor 1.8E-04 0.499 0.846
MIR221 microRNA 221 0.449 0.846
EDA Q92838 ectodysplasin A 0.97 0.553 0.808
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808
OTX2 P32243 orthodenticle homeobox 2 Transcription factor 0.92 0.514 0.808
PITX2 Q99697 paired like homeodomain 2 0.98 0.489 0.808
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
ADAMTS2 O95450 ADAM metallopeptidase with thrombospondin type 1 motif 2 Enzyme 0.97 0.579 0.808