Disease: Neurodegenerative Disorders
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885
PLB1 Q6P1J6 phospholipase B1 1.7E-72 0.488 0.846
DNAH8 Q96JB1 dynein axonemal heavy chain 8 Enzyme 1.1E-60 0.556 0.731
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
WFS1 O76024 wolframin ER transmembrane glycoprotein 1.6E-38 0.528 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
PDIA2 Q13087 protein disulfide isomerase family A member 2 8.5E-33 0.638 0.692
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CAPN2 P17655 calpain 2 Enzyme 3.5E-22 0.590 0.692
SLC18A1 P54219 solute carrier family 18 member A1 Transporter 2.8E-21 0.647 0.462
NLRP1 Q9C000 NLR family pyrin domain containing 1 5.0E-19 0.502 0.769
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
CABIN1 Q9Y6J0 calcineurin binding protein 1 Enzyme modulator 3.3E-17 0.536 0.846
GPRC6A Q5T6X5 G protein-coupled receptor class C group 6 member A G-protein coupled receptor 5.6E-17 0.526 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
TRPV1 Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 1.0E-16 0.446 0.885
PADI1 Q9ULC6 peptidyl arginine deiminase 1 2.0E-15 0.644 0.692
ITGB2 P05107 integrin subunit beta 2 Receptor 5.1E-15 0.444 0.923
GALC P54803 galactosylceramidase 5.2E-15 0.604 0.615
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885