Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
CD38 | P28907 | CD38 molecule | Enzyme | 2.3E-06 | 0.407 | 0.885 |
AFP | P02771 | alpha fetoprotein | Transporter | 1.1E-11 | 0.429 | 0.885 |
BCR | P11274 | BCR activator of RhoGEF and GTPase | Enzyme modulator | 0.99 | 0.431 | 0.885 |
C3 | P01024 | complement C3 | Enzyme modulator | 0.90 | 0.445 | 0.885 |
SHH | Q15465 | sonic hedgehog signaling molecule | 0.98 | 0.461 | 0.846 | |
TNFRSF8 | P28908 | TNF receptor superfamily member 8 | 0.86 | 0.444 | 0.808 | |
ATG5 | Q9H1Y0 | autophagy related 5 | Transporter | 0.98 | 0.462 | 0.885 |
TFAP2A | P05549 | transcription factor AP-2 alpha | Transcription factor | 0.99 | 0.488 | 0.769 |
MUC16 | Q8WXI7 | mucin 16, cell surface associated | 8.3E-112 | 0.479 | 0.808 | |
PPP1R2C | O14990 | PPP1R2C family member C | Enzyme modulator | 0.478 | 0.846 | |
ASPM | Q8IZT6 | abnormal spindle microtubule assembly | 3.4E-49 | 0.526 | 0.769 | |
AKR1C3 | P42330 | aldo-keto reductase family 1 member C3 | Enzyme | 7.6E-24 | 0.529 | 0.769 |
MSX2 | P35548 | msh homeobox 2 | Transcription factor | 0.26 | 0.539 | 0.769 |
ASPA | P45381 | aspartoacylase | 4.1E-04 | 0.564 | 0.731 | |
MIR99A | microRNA 99a | 0.536 | 0.808 | |||
VANGL1 | Q8TAA9 | VANGL planar cell polarity protein 1 | 2.0E-02 | 0.570 | 0.538 | |
ZSWIM6 | Q9HCJ5 | zinc finger SWIM-type containing 6 | 1.00 | 0.626 | 0.577 |