Disease: 21-hydroxylase deficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CAPN10 Q9HC96 calpain 10 Enzyme 6.9E-13 0.621 0.577
C4B_2 P0C0L4 P0C0L5 complement component 4B (Chido blood group), copy 2 0.670 0.731
C4A P0C0L4 P0C0L5 complement C4A (Rodgers blood group) Enzyme modulator 1.5E-11 0.563 0.769
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769
GLO1 Q04760 glyoxalase I 9.7E-07 0.537 0.769
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769
POR P16435 cytochrome p450 oxidoreductase 3.4E-10 0.502 0.769
C4B P0C0L4 P0C0L5 complement C4B (Chido blood group) Enzyme modulator 0.83 0.603 0.808
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ARR3 P36575 arrestin 3 Enzyme modulator 0.10 0.460 0.846
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
NR3C2 P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 0.84 0.469 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
NR1I3 Q14994 nuclear receptor subfamily 1 group I member 3 Nuclear receptor 3.5E-08 0.448 0.846
TRIM13 O60858 tripartite motif containing 13 0.64 0.462 0.846
CXADRP1 CXADR pseudogene 1 0.463 0.846