Disease: Alloxan Diabetes
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NKX6-1 P78426 NK6 homeobox 1 Transcription factor 6.3E-02 0.760 0.231
PCSK2 P16519 proprotein convertase subtilisin/kexin type 2 Enzyme 1.00 0.663 0.462
GPD2 P43304 glycerol-3-phosphate dehydrogenase 2 Enzyme 8.1E-11 0.678 0.538
ATP2A3 Q93084 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 Transporter 2.2E-09 0.617 0.577
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615
PDX1 P52945 pancreatic and duodenal homeobox 1 1.8E-02 0.530 0.654
IRS2 Q9Y4H2 insulin receptor substrate 2 0.99 0.535 0.654
ID1 P41134 inhibitor of DNA binding 1, HLH protein Transcription factor 3.1E-04 0.544 0.692
SLC2A2 P11168 solute carrier family 2 member 2 Transporter 3.4E-08 0.572 0.692
HK1 P19367 hexokinase 1 Kinase 0.91 0.542 0.731
CYBA P13498 cytochrome b-245 alpha chain 8.9E-06 0.520 0.769
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769
PAX6 P26367 paired box 6 1.00 0.450 0.769
SLC2A4 P14672 solute carrier family 2 member 4 Transporter 4.7E-05 0.528 0.769
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808
CPT1A P50416 carnitine palmitoyltransferase 1A Enzyme 5.1E-09 0.555 0.808
GCK P35557 glucokinase Kinase 0.63 0.523 0.808
IAPP P10997 islet amyloid polypeptide Signaling 3.2E-03 0.507 0.808
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
NEUROD1 Q13562 neuronal differentiation 1 Enzyme 0.77 0.543 0.808
S100A6 P06703 S100 calcium binding protein A6 Calcium-binding protein 0.18 0.510 0.808
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846