Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ALB P02768 albumin Transporter 0.64 0.317 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962