Disease: Alcohol Use Disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
EBPL Q9BY08 EBP like Enzyme 7.8E-05 0.615 0.577
ELK3 P41970 ETS transcription factor ELK3 Transcription factor 8.4E-02 0.490 0.846
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
LEP P41159 leptin 0.46 0.349 0.846
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808