Disease: Leukodystrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AARS2 Q5JTZ9 alanyl-tRNA synthetase 2, mitochondrial Nucleic acid binding 5.0E-17 0.644 0.500
ADAR P55265 adenosine deaminase RNA specific Enzyme 2.6E-02 0.501 0.808
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923
ATN1 P54259 atrophin 1 1.00 0.409 0.885
COX10 Q12887 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 Enzyme 8.4E-02 0.623 0.654
COX15 Q7KZN9 cytochrome c oxidase assembly homolog COX15 1.1E-13 0.638 0.538
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
CTC1 Q2NKJ3 CST telomere replication complex component 1 1.6E-11 0.601 0.538
DARS2 Q6PI48 aspartyl-tRNA synthetase 2, mitochondrial Enzyme 9.8E-13 0.638 0.577
DEGS1 O15121 delta 4-desaturase, sphingolipid 1 0.14 0.621 0.731
ECHS1 P30084 enoyl-CoA hydratase, short chain 1 Enzyme 8.8E-04 0.601 0.654
EIF2B1 Q14232 eukaryotic translation initiation factor 2B subunit alpha 7.6E-05 0.663 0.538
EIF2B2 P49770 eukaryotic translation initiation factor 2B subunit beta 2.1E-10 0.647 0.538
EIF2B4 Q9UI10 eukaryotic translation initiation factor 2B subunit delta 0.96 0.659 0.538
EIF2B5 Q13144 eukaryotic translation initiation factor 2B subunit epsilon 6.4E-02 0.615 0.769
ERCC8 Q13216 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 2.8E-15 0.551 0.885
FA2H Q7L5A8 fatty acid 2-hydroxylase Enzyme 0.15 0.573 0.654
FAM126A Q9BYI3 family with sequence similarity 126 member A 0.12 0.682 0.423
FOXRED1 Q96CU9 FAD dependent oxidoreductase domain containing 1 Enzyme 2.0E-16 0.633 0.462
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
GJC2 Q5T442 gap junction protein gamma 2 Cell-cell junction 1.0E-02 0.593 0.692
GLRX5 Q86SX6 glutaredoxin 5 Enzyme 0.75 0.659 0.538
HEPACAM Q14CZ8 hepatic and glial cell adhesion molecule 0.87 0.621 0.500
LIPT1 Q9Y234 lipoyltransferase 1 Enzyme 3.8E-08 0.674 0.462