Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
SOD2 | P04179 | superoxide dismutase 2 | Enzyme | 0.15 | 0.379 | 0.923 |
COMT | P21964 | catechol-O-methyltransferase | Enzyme | 1.1E-06 | 0.400 | 0.923 |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | |
LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
GPX1 | P07203 | glutathione peroxidase 1 | Enzyme | 3.9E-05 | 0.458 | 0.923 |
CD69 | Q07108 | CD69 molecule | 3.0E-02 | 0.488 | 0.923 | |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
MAPK3 | P27361 | mitogen-activated protein kinase 3 | Kinase | 3.7E-02 | 0.379 | 0.885 |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
CASP1 | P29466 | caspase 1 | Enzyme | 3.5E-05 | 0.413 | 0.885 |
CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 |