Disease: Generalized seizures
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
EZR P15311 ezrin Cellular structure 0.18 0.476 0.808
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
TRH P20396 thyrotropin releasing hormone 8.9E-04 0.519 0.846
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
KDM5B Q9UGL1 lysine demethylase 5B Epigenetic regulator 7.9E-15 0.532 0.731