Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
LMNA P02545 lamin A/C 1.00 0.384 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885