Disease: Increased serum lactate
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LIPT2 A6NK58 lipoyl(octanoyl) transferase 2 0.63 0.821 0.154
PMPCB O75439 peptidase, mitochondrial processing subunit beta Enzyme 4.5E-08 0.769 0.192
GFM2 Q969S9 G elongation factor mitochondrial 2 Enzyme 1.5E-18 0.736 0.269
SLC25A42 Q86VD7 solute carrier family 25 member 42 Transporter 0.49 0.760 0.269
UQCRQ O14949 ubiquinol-cytochrome c reductase complex III subunit VII 4.8E-02 0.722 0.308
PNPLA8 Q9NP80 patatin like phospholipase domain containing 8 1.1E-02 0.792 0.308
MRPS34 P82930 mitochondrial ribosomal protein S34 2.6E-03 0.722 0.346
NDUFA9 Q16795 NADH:ubiquinone oxidoreductase subunit A9 Enzyme 4.8E-03 0.653 0.385
NDUFA10 O95299 NADH:ubiquinone oxidoreductase subunit A10 Enzyme 6.2E-08 0.678 0.385
COQ8A Q8NI60 coenzyme Q8A Kinase 9.3E-11 0.674 0.385
SERAC1 Q96JX3 serine active site containing 1 3.9E-06 0.686 0.385
TRNV tRNA 0.670 0.423
TSFM P43897 Ts translation elongation factor, mitochondrial Nucleic acid binding 1.9E-09 0.736 0.423
COQ9 O75208 coenzyme Q9 5.5E-06 0.700 0.423
CARS2 Q9HA77 cysteinyl-tRNA synthetase 2, mitochondrial Enzyme 9.6E-08 0.700 0.423
NDUFA4 O00483 NDUFA4 mitochondrial complex associated Enzyme 2.4E-02 0.695 0.462
LIPT1 Q9Y234 lipoyltransferase 1 Enzyme 3.8E-08 0.674 0.462
FOXRED1 Q96CU9 FAD dependent oxidoreductase domain containing 1 Enzyme 2.0E-16 0.633 0.462
NDUFA12 Q9UI09 NADH:ubiquinone oxidoreductase subunit A12 7.4E-05 0.659 0.462
NDUFAF5 Q5TEU4 NADH:ubiquinone oxidoreductase complex assembly factor 5 3.1E-10 0.674 0.462
PNPT1 Q8TCS8 polyribonucleotide nucleotidyltransferase 1 Enzyme 4.0E-04 0.653 0.462
SDHAF1 A6NFY7 succinate dehydrogenase complex assembly factor 1 8.7E-02 0.656 0.462
NDUFV2 P19404 NADH:ubiquinone oxidoreductase core subunit V2 5.6E-03 0.610 0.500
HIBCH Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase Enzyme 2.6E-13 0.700 0.500
AARS2 Q5JTZ9 alanyl-tRNA synthetase 2, mitochondrial Nucleic acid binding 5.0E-17 0.644 0.500