Disease: Neuromyelitis Optica
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IFNB1 P01574 interferon beta 1 0.421 0.846
NM neutrophil migration 0.473 0.808
CDR3 Cerebellar degeneration-related autoantigen-3 0.472 0.808
MIR326 microRNA 326 0.560 0.731
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
FCRL3 Q96P31 Fc receptor like 3 Cell adhesion 6.0E-21 0.612 0.769
HLA-G P17693 major histocompatibility complex, class I, G 1.4E-11 0.461 0.769
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
FCGR3A P08637 Fc fragment of IgG receptor IIIa Cell adhesion 3.7E-06 0.432 0.962
TLR9 Q9NR96 toll like receptor 9 9.8E-06 0.411 0.885
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885
IRF5 Q13568 interferon regulatory factor 5 Transcription factor 9.0E-03 0.489 0.731
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962