Disease: Primary Sjögren's syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IL2 P60568 interleukin 2 0.48 0.336 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
IFNA1 P01562 interferon alpha 1 0.371 0.923
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
IFNA13 P01562 interferon alpha 13 0.374 0.923
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885