Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846
KDM6A O15550 lysine demethylase 6A Epigenetic regulator 1.00 0.498 0.769
ARHGEF2 Q92974 Rho/Rac guanine nucleotide exchange factor 2 1.00 0.502 0.769
TET1 Q8NFU7 tet methylcytosine dioxygenase 1 1.00 0.523 0.808
SLC12A5 Q9H2X9 solute carrier family 12 member 5 Transporter 1.00 0.570 0.654
CASZ1 Q86V15 castor zinc finger 1 Transcription factor 1.00 0.553 0.731
SRRM2 Q9UQ35 serine/arginine repetitive matrix 2 1.00 0.564 0.692
MAP1B P46821 microtubule associated protein 1B Cellular structure 1.00 0.628 0.500
ATP2B2 Q01814 ATPase plasma membrane Ca2+ transporting 2 Transporter 1.00 0.659 0.731