Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
IL2 P60568 interleukin 2 0.48 0.336 0.885
LEP P41159 leptin 0.46 0.349 0.846
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
H3P10 H3 histone pseudogene 10 0.350 0.846
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846