Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
CFH P08603 complement factor H 0.86 0.441 0.885
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
EPHX2 P34913 epoxide hydrolase 2 Enzyme 1.8E-21 0.568 0.654
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
PDE5A O76074 phosphodiesterase 5A 1.1E-04 0.513 0.731
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SEMA6A Q9H2E6 semaphorin 6A Signaling 1.00 0.486 0.808
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962