Disease: Primary Sjögren's syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IL2 P60568 interleukin 2 0.48 0.336 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
IFNA1 P01562 interferon alpha 1 0.371 0.923
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
IFNA13 P01562 interferon alpha 13 0.374 0.923