Disease: Hypospadias
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WHCR Wolf-Hirschhorn syndrome chromosome region 0.638 0.577
H19 H19 imprinted maternally expressed transcript 0.494 0.923
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731
RTTN Q86VV8 rotatin 9.0E-34 0.619 0.654
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
FANCL Q9NW38 FA complementation group L Enzyme 5.9E-23 0.551 0.731
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
POR P16435 cytochrome p450 oxidoreductase 3.4E-10 0.502 0.769
RFWD3 Q6PCD5 ring finger and WD repeat domain 3 Enzyme 3.5E-10 0.569 0.731
ESCO2 Q56NI9 establishment of sister chromatid cohesion N-acetyltransferase 2 3.2E-07 0.581 0.615
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
LETM1 O95202 leucine zipper and EF-hand containing transmembrane protein 1 Transporter 1.2E-06 0.545 0.692