Disease: Steroid Sulfatase Deficiency Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MTAP Q13126 methylthioadenosine phosphorylase Enzyme 7.6E-08 0.514 0.731
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
LAG3 P18627 lymphocyte activating 3 Receptor 0.28 0.517 0.692
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HEATR3 Q7Z4Q2 HEAT repeat containing 3 3.5E-07 0.700 0.231
HCCS P53701 holocytochrome c synthase Enzyme 0.89 0.559 0.731